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The use of a new carboranylamidophosphite ligand in the asymmetric Pd-catalysed allylic alkylation in organic solvents and supercritical carbon dioxide |
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| Authors: | Sergey E. Lyubimov Ilya V. Kuchurov Andrey A. Tyutyunov Vadim A. Davankov |
| Affiliation: | a A.N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, Vavilov Street 28, 119991 Moscow, Russia b N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Leninsky Prosp. 47, 119991 Moscow, Russia |
| Abstract: | A novel P-monodentate ligand based on carboranyl alcohol and (S)-2-(anilinomethyl)pyrrolidine provides high enantioselectivities (ee’s up to 95%) in the Pd-catalyzed allylic alkylation of (E)-1,3-diphenylallyl acetate. The first example of the Pd-catalysed allylic alkylation in supercritical carbon dioxide is also described. |
| Keywords: | Asymmetric allylic alkylation Palladium Supercritical carbon dioxide Carboranyldiamidophosphite |
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