Total synthesis of citrafungin A |
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| Authors: | Calo Frederick Richardson Jeffery Barrett Anthony G M |
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| Affiliation: | Department of Chemistry, Imperial College London, Exhibition Road, London SW7 2AZ, England. |
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| Abstract: | The antifungal natural product citrafungin A was synthesized using, as key steps, an asymmetric aldol reaction of a chiral oxazolidinone, diastereoselective alkylation of a chiral 1,3-dioxolan-2-one, semihydrogenation of an enyne, and selective methyl ester deprotection. |
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