| 2,6-二溴-4-氨基吡啶的合成 |
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| 引用本文： | 钮倩倩,潘利华,李珍,马世盐,谢文兵,林敏,付强.2,6-二溴-4-氨基吡啶的合成[J].分子科学学报,2006,22(6):401-404. |
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| 作者姓名： | 钮倩倩 潘利华 李珍 马世盐 谢文兵 林敏 付强 |
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| 作者单位： | 1. 东北师范大学化学学院,吉林,长春,130024
2. 中国科学院长春应用化学研究所国家电化学光谱分析研究中心,吉林,长春,130022 |
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| 摘 要： | 从时间分辨荧光免疫分析双功能螯合剂合成需要出发,设计了2,6-二溴-4-氨基吡啶的合成路线.以2,6-二溴吡啶为起始原料,经过氧化、硝化和还原三步合成了该化合物,通过红外光谱、元素分析和熔点测定对其进行了表征.证明了该结构和合成方法的可靠性,并分别探讨了各步产物合成反应条件的影响,具有一定的参考价值.
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| 关 键 词： | 时间分辨荧光免疫分析 2 6-二溴-4-氨基吡啶 |
| 文章编号： | 1000-9035(2006)06-0401-04 |
| 收稿时间： | 06 27 2006 12:00AM |
| 修稿时间： | 2006年6月27日 |
Preparation of 2,6-dibromo-4-aminopyridine |
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| NIU Qian-qian,PAN Li-hua,LI Zhen,MA Shi-yan,XIE Wen-bing,LIN Min,FU Qiang.Preparation of 2,6-dibromo-4-aminopyridine[J].Journal of Molecular Science,2006,22(6):401-404. |
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| Authors: | NIU Qian-qian PAN Li-hua LI Zhen MA Shi-yan XIE Wen-bing LIN Min FU Qiang |
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| Institution: | 1. Faculty of Chemistry,Northeast Normal University,Changchun 130024. China; 2. National Analytical Research Center of Electrochemistry and Spectroscopy, Changchun Institute of Applied Chemistry, Chinese Academy of Science, Changchun 130022, China |
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| Abstract: | The synthetic route of 2,6-dibromo-4-aminopyridine was designed with the aim to satisfy the need of bifunctional chelates of time-resolved fluorescence immunoassay.It was prepared from 2,6-dibromopyridine by oxidation,nitration and reduction.The structure of this product was determined by IR,element analysis and melting point.The result proved the reliability of this product and the synthetic method.The reaction conditions was also invertigated. |
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| Keywords: | time-resolved fluorescence immunoassay 2 6-dibromo-4-amino-pyridine |
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