A new approach to the ferritin iron core growth: influence of the H/L ratio on the core shape |
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| Authors: | López-Castro J D Delgado J J Perez-Omil J A Gálvez Natividad Cuesta Rafael Watt Richard K Domínguez-Vera José M |
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| Institution: | Departamento Ciencia de Materiales e Ingeniería Metalúrgica y Química Inorgánica, Universidad de Cádiz, Campus Río San Pedro, 11510, Cádiz, Spain. |
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| Abstract: | An electron microscopy study, in combination with modeling and image simulation, of four different reconstituted ferritin samples: recombinant human H and L homopolymers, and H and L heteropolymers of native L-subunit-rich horse spleen and H-subunit-rich human heart ferritins, points out the existence of a correlation between iron core shape and protein shell. |
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