A facile enantioselective synthesis of enantiomerically pure (R)-phenoxybenzamine hydrochloride using the hydrolytic kinetic resolution method |
| |
| Authors: | Milind D. Nikalje Murugesan Sasikumar Murugan Muthukrishnan |
| |
| Affiliation: | 1. Department of Chemistry, University of Pune, Pune 411 007, India;2. Division of Organic Chemistry, National Chemical Laboratory, Pune 411 008, India |
| |
| Abstract: | A practical and highly efficient enantioselective synthesis of (R)-phenoxybenzamine hydrochloride has been described for the first time using Jacobsen’s hydrolytic kinetic resolution of a terminal epoxide as a key step and source of chirality. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
