Asymmetric synthesis of chiral spiro bis(isoxazoline) and spiro (isoxazole–isoxazoline) ligands |
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| Authors: | Kazuhiro Takenaka Toyohiro Nagano Shinobu Takizawa Hiroaki Sasai |
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| Institution: | The Institute of Scientific and Industrial Research (ISIR), Osaka University, Mihogaoka, Ibaraki, Osaka 567-0047, Japan |
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| Abstract: | Asymmetric synthesis of novel chiral ligands, bis(isoxazoline) on a spiro4.4]nonane scaffold and isoxazole–isoxazoline on a spiro4.5]decane scaffold, has been achieved by utilizing an enantiomerically pure alcohol as the starting material. |
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