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Heterocyclic synthesis using nitrilimines. Part 13: Synthesis of new1,2,3,4-tetrahydro-s-tetrazine derivatives
Authors:Hany M.M. Dalloul
Affiliation:Department of Chemistry, Faculty of Applied Science, Al-Aqsa University of Gaza, PO Box 4051, Gaza 76888, Palestine, Israel
Abstract:The reaction of C-aroyl-N-arylnitrilimines with 1,1-dimethylhydrazine or 1-methyl-1-phenylhydrazine led to the formation of the acyclic electrophilic addition products, which underwent thermal oxidative cyclization at CH3 to 1,2,3,4-tetrahydro-s-tetrazines. Both analytical and spectroscopic data of all the synthesized compounds are in full agreement with the proposed structures.
Keywords:s-Tetrazines   Formazanes   Nitrilimines   Electrophilic addition   Cyclization
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