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Direct asymmetric aldol reaction using MBHA resin-supported peptide containing L-proline unit |
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| Authors: | Liang Zhang Wen Bo Ding Yong Ping Yu Hong Bin Zou Institute of Materia Medica College of Pharmaceutical Sciences Zhejiang University Hangzhou China |
| Affiliation: | Institute of Materia Medica, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China |
| Abstract: | MBHA resin-supported tripeptide catalyst system containing L-proline unit has been developed for use in the direct asymmetric aldol reaction of acetone and aldehydes,which afford the corresponding products with satisfactory isolated yields and enantiomeric excesses. |
| Keywords: | Direct asymmetric aldol reaction MBHA resin-supported peptide L-Proline " Tea-bag" methodology |
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