3D-ASL灌注成像与静息态功能MRI在癫痫诊断及鉴别中的价值

选取123例癫痫患者作为研究组,同期69例健康体检者作为对照组,均行三维动脉自旋标记技术(3D-ASL)灌注成像与静息态功能MRI(rs-FMRI)检查,研究二者在癫痫病诊断及鉴别中的价值.结果发现,研究组全面发作脑血流量(CBF)、低频振幅(ALFF)＜部分发作和对照组,全面发作血清脑源性神经细胞营养因子(BDNF)...

The Value of 3D-ASL Perfusion Imaging and Resting State MRI in Diagnosis and Differentiation of Epilepsy

A total of 123 patients with epilepsy were selected as the research group,and 69 healthy physical examination subjects were selected as the control group during the same period,the value of two methods in diagnosis and differentiation of epilepsy was studied.All were performed with three-dimensional arterial spin labeling technique(3D-ASL)perfusion imaging and resting state functional magnetic resonance imaging(rs-FMRI)examination.It was found that the full-onset cerebral blood flow(CBF)and low-frequency amplitude(ALFF)of the research grouppartial seizure>control group(P<0.05);and CBF and ALFF in patients with epilepsy were positively correlated with BDNF,IGF-1,MMSE,and negatively correlated with NPY.The combination of CBF and ALFF had high application value in diagnosing seizures and identifying different types of seizures.It can be seen that 3D-ASL perfusion imaging and rs-FMRI have high application value in the diagnosis and identification of seizure types.