A highly selective synthesis of 3-hydroxy-2-methylpropionamide involving a one-pot tandem hydroformylation-hydrogenation sequence |
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| Authors: | García Luis Claver Carmen Diéguez Montserrat Masdeu-Bultó Anna M |
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| Affiliation: | Departament de Química Física i Inorgànica, Universitat Rovira i Virgili, Campus Sescelades, Tarragona, Spain. |
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| Abstract: | 3-Hydroxy-2-methylpropionamide, an important intermediate in the synthesis of methyl methacrylate, has been obtained with excellent conversion and high selectivity from acrylamide by a tandem hydroformylation-hydrogenation sequence catalysed by Rh/PPh3 and Raney Ni, respectively. |
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