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4-Hydroxy-2-quinolones. 111. Simple synthesis of 1-substituted 4-methyl-2-oxo-1,2-dihydroquinoline-3-carboxylic acids
Authors:I V Ukrainets  O V Gorokhova  L V Sidorenko  N L Bereznyakova
Institution:(1) National Pharmaceutical University, Kharkiv, 61002, Ukraine
Abstract:A preparative method of obtaining 1-substituted 4-methyl-2-oxo-1,2-dihydroquinoline-3-carboxylic acids is proposed. Features of their spatial structure have been studied. __________ Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 1, pp. 69–74, January, 2007.
Keywords:1-R-4-methyl-2-oxo-1  2-dihydroquinoline-3-carboxylic acid  4-chloroquinolin-2-one  cyanoacetic ester  amidation  hydrolysis  decarboxylation  X-ray structural analysis
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