Affiliation: | 1. Merck, West Point, PA, USAMerck & Company Incorporation, 70 Sumneytown Pike, WP82–30, West Point, PA 19486, USA Fax: +1‐215‐652‐3499===;2. Johnson and Johnson Pharmaceutical R&D, L.L.C., Springhouse, PA, USA;3. Drexel University, Philadelphia, PA, USA |