Synthesis of Highly Functionalized γ‐Lactones via 1,5‐Electrocyclic Ring Closure |
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| Authors: | Olcay Ana F&#x;eyma Güngr Gke Merey |
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| Institution: | Olcay Anaç,F. Şeyma Güngör,Gökçe Merey |
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| Abstract: | We have investigated 1,5‐electrocyclic ring‐closure reactions of conjugated esters with dimethyl diazomalonate in the presence of Cu(acac)2] as catalyst. Our new protocol offers an easy entry to various polyfunctionalized γ‐lactones in high yields. Their subsequent derivatives may be used as valuable intermediates, especially in the synthesis of natural products and their analogues. |
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| Keywords: | γ ‐Lactones Ylides Diazo compounds Carbenes 1 5‐Electrocyclic ring closure Ring closure |
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