Highly chromic, proton-responsive phenyl pyrimidones |
| |
Authors: | Dhuguru Jyothi Gheewala Chirag Kumar N S Saleesh Wilson James N |
| |
Institution: | Department of Chemistry, University of Miami, 1301 Memorial Drive, Coral Gables, Florida 33124, USA. |
| |
Abstract: | Aryl pyrimidones are pharmacologically relevant compounds whose optical properties have only been partially explored. We report the synthesis and optical characterization of a series of aryl- and diaryl-2(1H)-pyrimidones. The electronic transitions of these chromophores are modulated by the extent of conjugation between the pendant phenyl ring and the pyrimidone core as well as the presence of electron-donating auxochromes. Monoprotonation of the pyrimidone ring results in large hyperchromic and bathochromic shifts as well as switching of fluorescence making these phenyl pyrimidones of interest as sensory materials. |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|