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Lewis base catalyzed ring opening of aziridines with silylated nucleophiles
Authors:Minakata Satoshi  Okada Yuriko  Oderaotoshi Yoji  Komatsu Mitsuo
Institution:Department of Applied Chemistry, Graduate School of Engineering, Osaka University, Yamadaoka 2-1, Suita, Osaka 565-0871, Japan.
Abstract:The ring opening of N-tosylaziridines with trimethylsilylated nucleophiles, catalyzed by N,N,N',N'-tetramethylethylenediamine, led to the production of beta-functionalized sulfonamides in good to excellent yields with high regioselectivity. reaction: see text]
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