Lewis base catalyzed ring opening of aziridines with silylated nucleophiles |
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Authors: | Minakata Satoshi Okada Yuriko Oderaotoshi Yoji Komatsu Mitsuo |
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Institution: | Department of Applied Chemistry, Graduate School of Engineering, Osaka University, Yamadaoka 2-1, Suita, Osaka 565-0871, Japan. |
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Abstract: | The ring opening of N-tosylaziridines with trimethylsilylated nucleophiles, catalyzed by N,N,N',N'-tetramethylethylenediamine, led to the production of beta-functionalized sulfonamides in good to excellent yields with high regioselectivity. reaction: see text] |
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