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A Novel Strategy for Determination of Paracetamol in the Presence of Morphine Using a Carbon Paste Electrode Modified with CdO Nanoparticles and Ionic Liquids
Authors:Somaye Cheraghi  Mohammad Ali Taher  Hassan Karimi‐Maleh
Institution:1. Department of Chemistry, Shahid Bahonar University of Kerman, Iran;2. Department of Chemistry, Graduate University of Advanced Technology, Kerman, Iran, Tel.: +98?9112540112
Abstract:A voltammetric sensor for determination of paracetamol in the presence of morphine is described for the first time. The synthesized CdO nanoparticles were characterized with different methods such as scanning electron microscopy (SEM) and X‐ray diffraction (XRD). The paracetamol and morphine peaks are separated ca. 0.37 and 0.65 V, respectively; hence paracetamol can be analysed in the presence of morphine and more than 21 times of the current excess of paracetamol. The detection limits for paracetamol and morphine were 0.07 and 0.1 μM, respectively. The sensor has been successfully applied for the assay of the above compounds in real samples.
Keywords:Paracetamol  Morphine  CdO nanoparticles  Ionic liquid  Voltammetric sensor
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