Chiral Recognition of Tryptophan Enantiomers Based on β‐Cyclodextrin‐platinum Nanoparticles/Graphene Nanohybrids Modified Electrode |
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Authors: | Juanjuan Xu Qinghong Wang Chunzhi Xuan Qiao Xia Xia Lin Yingzi Fu |
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Affiliation: | Laboratory of Luminescence and Real‐Time Analysis (Southwest University), Ministry of Education, College of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, China |
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Abstract: | The nanohybrids which based on β‐cyclodextrin, platinum nanoparticles and graphene (β‐CD‐PtNPs/GNs) were successfully synthesized and characterized by scanning electron microscopy (SEM), transmission electron microscopy (TEM), fourier transform infrared spectroscopy (FT‐IR) and electrochemical impedance spectroscopy (EIS). Then they were used to construct a simple and reliable chiral sensing platform to interact with tryptophan (Trp) enantiomers. Differential pulse voltammetry (DPV) was used to investigate the stereo selectivity of β‐CD‐PtNPs/GNs to Trp enantiomers. After interaction, the obvious difference of peak currents of L‐Trp and D‐Trp was obtained, indicating this strategy could be employed to chiral recognition of Trp enantiomers. Under the optimum conditions, the chiral sensor exhibited a good linear response to Trp enantiomers in a linear range of 5.0×10?5 to 5.0×10?3 M with a low limit of detection of 1.7×10?5 M (S/N=3). This approach provided a new available platform to recognize and determine Trp enantiomers. |
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Keywords: | Chiral recognition Nanohybrids Tryptophan enantiomers Electrochemical methods |
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