Passive or active fluctuations in membranes containing proteins |
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Authors: | Girard P Prost J Bassereau P |
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Institution: | PhysicoChimie Curie, UMR CNRS-Institut Curie 168, 11 rue Pierre et Marie Curie, 75231 Paris CEDEX 05, France. |
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Abstract: | We have experimentally investigated the effect of a transmembrane protein, the Ca2+-ATPase, on shape fluctuations of giant vesicles. By using the micropipette method, we have measured a substantial renormalization of the bending modulus due to the presence of proteins in the membrane. Moreover, we have produced the first quantitative measurement of the active force dipole associated with the amplification of the fluctuations when the proteins are activated by adenosine 5'-triphosphate (ATP). |
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