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High-resolution magic angle spinning NMR of the neuronal tau protein integrated in Alzheimer's-like paired helical fragments
Authors:Sillen Alain  Wieruszeski Jean-Michel  Leroy Arnaud  Younes Amena Ben  Landrieu Isabelle  Lippens Guy
Affiliation:CNRS - Université de Lille 2 UMR 8525 and Inserm IFR17, Institut Pasteur de Lille, BP 245 - F-59019 Lille Cedex, France.
Abstract:HRMAS NMR of tau paired helical fragments assembled with heparin show an intensity decrease for those amino acids that are incorporated into the rigid core region, whereas the N-terminal amino acids maintain their full mobility.
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