Palladium-catalyzed highly regio- and stereoselective addition of organoboronic acids to allenes in the presence of AcOH |
| |
| Authors: | Ma Shengming Jiao Ning Ye Longwu |
| |
| Affiliation: | State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 354 Fenglin Lu, Shanghai 200032, P. R. China. masm@mail.sioc.ac.cn |
| |
| Abstract: | The Pd(0)-catalyzed regio- and stereoselective addition of organoboronic acids to allenes leads to stereodefined tri- or tetrasubstituted alkenes. Furthermore, this method shows high substitutent-loading capability and tolerance of various substitutents. A hydropalladation-Suzuki coupling mechanism, which may account for the regio- and stereoselectivity, is proposed. |
| |
| Keywords: | alkenes allenes organoboronic acids palladium |
| 本文献已被 PubMed 等数据库收录！ |
|
