Sanraku-Ocean Co., Ltd., Central Research Laboratories, Johnan, Fujisawa 251, Japan;Institute of Microbial Chemistry, Kamiosaki, Shinagawa, Tokyo 141, Japan
Abstract:
The tricyclic quinone 8 was successfully synthesized from naphthazalin, and the total synthesis of (±)-2-hydroxyaklavinone via 8 was accomplished in an overall yield of about 18% through the regio-controlled route.