Synthesis of lipoxins: Total synthesis of conjugated trihydroxy eicosatetraenoic acids |
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Authors: | Julian Adams Brian J. Fitzsimmons Joshua Rokach |
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Affiliation: | Merck Frosst Canada Inc., P.O. Box 1005, Pointe Claire/Dorval Quebec, Canada H9R 4P8 |
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Abstract: | The first synthesis of a conjugated trihydroxy eicosatetraenoic acid, a possible structure for Lipoxin A is described. A biomimetic approach was utilized. |
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