Enzymatic study of the late stages of protoberberine alkaloid biosynthesis |
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Authors: | C.W.W. Beecher W.J. Kelleher |
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Affiliation: | University of Connecticut, School of Pharmacy, Storrs, CT 06268, U.S.A. |
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Abstract: | A specific methyltransferase which converts tetrahydrocolumbamine to tetrahydropalmatine, and oxidase activity which converts tetrahydroberberine, tetrahydrocolumbamine and tetrahydropalmatine, but not tetrahydrojatrorrhizine, to their quaternary counterparts are demonstrated. |
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