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From penicillin to penem and carbapenem. V Synthesis ofcarbapenam skeleton by (3 + 2) cyclization |
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| Authors: | Katsumi Fujimoto Yuji Iwano Koichi Hirai |
| Affiliation: | Chemical Research Laboratories, Sankyo Co., Ltd. 1-2-58, Hiromachi, Shinagawa-ku, Tokyo 140, Japan |
| Abstract: | The carbapenam derivatives were prepared by the new type of (3+2) cyclization2) of 4-iodomethyl-2-azetidinones (1 and 6) and 2-thiosubstituted dimethylfumarate derivatives (2, R= CH3, C6H5). |
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