Studies on chemical carcinogens and mutagens. XXVII alkylating property of mutagenic N-trimethylsilylmethyl-N-nitrosourea,a silicon-analogue of N-neopentyl-N-nitrosourea,in aqueous media |
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| Authors: | Shin-ichi Ninomiya Masakazu Ebie Atsushi Hakura Kohfuku Kohda Yutaka Kawazoe Takayuki Shioiri |
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| Affiliation: | Faculty of Pharmaceutical Sciences, Nagoya City University Tanabedori, Mizuho-ku, Nagoya 467, Japan |
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| Abstract: | The kinetics for hydrolysis and the chemoselectivity toward nucleophiles of mutagenic N-trimethylsilylmethyl-N-nitrosourea, a silicon analogue of N-neopentyl-N-nitrosourea, were studied. |
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