Improved procedure for the preparation of deoxynucleoside phosphoramidites: Arylphosphoramidites as new convenient intermediates for oligodeoxynucleotide synthesis |
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| Authors: | Jean-Louis Fourrey Jeannette Varenne |
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| Institution: | Institut de Chimie des Substances Naturelles , C.N.R.S., 91190-Gif sur Yvette, France |
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| Abstract: | A simplified procedure for the preparation of deoxynucleoside methyl- and arylphosphoramidites is described. Both types of phosphoramidites can be conveniently activated by N-methylaniline trifluoracetate for their use in oligodeoxynucleotide synthesis. |
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