Preparation of phosphinic acids: Michael additions of phosphonous acids/esters to conjugated systems. |
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Authors: | John K Thottathil Denis E Ryono Claire A Przybyla Jerome L Moniot Richard Neubeck |
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Institution: | The Squibb Institute for Medical Research P. O. Box 4000 Princeton, New Jersey 08540 U.S.A. |
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Abstract: | A very mild and facile method for the preparation of phosphinic acids via Michael addition of phosphonous acids as well as esters, through an intermediate silyl alkyl phosphonite, to activated conjugated systems is described. |
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