|
|||||
|
|
| 黑紫橐吾化学成分的分离与鉴定 | |
| 引用本文： | 施树云,赵昱,张宇平,黄可龙,刘素琴.黑紫橐吾化学成分的分离与鉴定[J].高等学校化学学报,2008,29(5):941-943. |
| 作者姓名： | 施树云 赵昱 张宇平 黄可龙 刘素琴 |
| 作者单位： | 1. 中南大学化学化工学院,长沙,410083;浙江大学药学院中药与天然药物研究室,杭州,310058 2. 浙江大学药学院中药与天然药物研究室,杭州,310058 3. 中南大学化学化工学院,长沙,410083 |
| 摘 要： | 利用各种色谱技术对黑紫橐吾的乙酸乙酯萃取部位进行分离纯化, 并且根据一维和二维波谱数据进行结构鉴定. 共分离得到4个呋喃雅槛蓝型倍半萜: 1α-氯-6β-异丁酰基-9-酮-10β-羟基-呋喃雅槛蓝烷(1), 1α-羟基-6β-异丁酰基-9-酮-10β-氢-呋喃雅槛蓝烷(2), 1α-羟基-6β-异丁酰基-9-酮-10α-氢-呋喃雅槛蓝烷(3)和1α,10β-二羟基-6β-当归酰基-9-酮-呋喃雅槛蓝烷(4). 其中化合物1为新化合物, 并且通过X射线单晶衍射确定了绝对构型; 化合物2~4为首次从该植物中分离得到. |
| 关 键 词： | 黑紫橐吾 分离纯化 结构鉴定 呋喃雅槛蓝型倍半萜 X射线衍射 |
| 收稿时间： | 2007-07-18 |
Separatian and Identification of Constituents from Ligularia atroviolacea |
|
| SHI Shu-Yun,ZHAO Yu,ZHANG Yu-Ping,HUANG Ke-Long,LIU Su-Qin.Separatian and Identification of Constituents from Ligularia atroviolacea[J].Chemical Research In Chinese Universities,2008,29(5):941-943. | |
| Authors: | SHI Shu-Yun ZHAO Yu ZHANG Yu-Ping HUANG Ke-Long LIU Su-Qin |
| Institution: | School of Chemistry and Chemical Engineering, Central South University, Changsha 410083, China;;Department of Traditional Chinese Medicine and Natural Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310031, China |
| Abstract: | A new and three known furanoeremophilanes were separated from Ligularia atroviolacea via chemical investigation, which were identified as 1α-chloro-6β-isobutyroxy-9-oxo-10β-hydroxy-furanoeremophilane(1), 1α-hydroxy-6β-isobutyroxy-9-oxo-10β-H-furanoeremophilane(2), 1α-hydroxy-6β-isobutyroxy-9-oxo-10α-H-furanoeremophilane(3), 1α,10β-dihydroxy-6β-angeloyloxy-9-oxo-furanoeremophilane(4). Their structures were established by spectroscopic methods including 2D-NMR. The absolute structure of compound 1 was determined by X-ray diffraction analysis. |
| Keywords: | Ligularia atroviolacea Isolation and purification Structure identification Furanoeremophilane X-ray diffraction |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |
| 点击此处可从《高等学校化学学报》浏览原始摘要信息 | |
| 点击此处可从《高等学校化学学报》下载免费的PDF全文 | |