Dipartimento di Scienze dell'Ambiente e del Territorio, Universita' di Milano, Via L. Emanueli, 15, I-20126, Milan, Italy
Abstract:
Three nitroarenes were submitted to Ru3(CO)12-catalyzed reductive carbonylation in acetonitrile and in cis-cyclooctene. The main reaction products were the corresponding amines, ureas and six- or five-membered cyclization products. Optimization of the reaction varying the temperature, the CO pressure, the catalyst/substrate ratio and the reaction time and a statistical analysis of conversion and selectivity data allow to suggest a reaction mechanism in some reaction conditions.