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Ruthenium-catalyzed cycloaddition of aryl azides and alkynes
Authors:Rasmussen Lars Kyhn  Boren Brant C  Fokin Valery V
Institution:Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA.
Abstract:The formation of 1,5-disubstituted 1,2,3-triazoles from aryl azides and alkynes was readily accomplished using Cp*RuCl]4 catalyst in dimethylformamide. It was also demonstrated that the reaction provided higher yields, cleaner product, and shorter reaction times when carried out under microwave irradiation.
Keywords:
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