| 无溶剂微波促进下1－苯基－3－甲基－5－吡唑啉酮与芳酰氯的反应研究 |
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| 引用本文： | 白银娟,路军,甘海婴,王振军,马怀让. 无溶剂微波促进下1－苯基－3－甲基－5－吡唑啉酮与芳酰氯的反应研究[J]. 有机化学, 2002, 22(9): 638-641 |
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| 作者姓名： | 白银娟 路军 甘海婴 王振军 马怀让 |
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| 作者单位： | 西北大学化学系,西安,710069 |
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| 基金项目： | 陕西省教育厅专项基金 (No.0 1JK2 0 5 )资助项目 |
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| 摘 要： | 无溶剂条件下，微波促进1－苯基－3－甲基－5－吡唑啉酮与等量的酰氯反应 ，可高产率简便得到5－酰化产物。在有氢氧化钙存在时与2倍量的酰氯反应主要得 到4，5－位酰化产物，产物结构经^1H NMR,^13C NMR,IR,MS及元素分析进行了表征。
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| 关 键 词： | 无溶剂 酰氯 微波辐射 酰化 吡唑酮 P 吡唑啉 P 酮 有机合成 红外光谱学 核磁共振 |
| 修稿时间： | 2001-09-17 |
Microwave-enhanced reaction of 1-phenyl-3-methylpyrazole-5-one with acid chlorides under solvent-free conditions |
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| Affiliation: | Department of Chemistry, Northwest University,Xi'an(710069) |
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| Abstract: | A microwave enhanced synthesis of 1 phenyl 3 methyl 5 acyloxypyrazoles from 1 phenyl 3 methylpyrazole 5 one with an equivalent of acid chlorides under solvent free conditions was achieved in moderate to good yields. 4 Acyl 5 acyloxypyrazoles were obtained with 2 equivalents of acid chlorides in the present of calcium hydroxide. Their structures were confirmed by 1H NMR, 13 C NMR, IR, MS and elemental analysis. |
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| Keywords: | microwave irradiation acylation 1 phenyl 3 methylpyrazole 5 one |
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