| Pd/C/PPh3:简单有效的双羰化反应催化体系 |
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| 引用本文： | 刘建明a,b,郑书展a,b,孙伟a,夏春谷a.Pd/C/PPh3:简单有效的双羰化反应催化体系[J].中国化学,2009,27(4):623-627. |
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| 作者姓名： | 刘建明a b 郑书展a b 孙伟a 夏春谷a |
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| 作者单位： | a羰基合成与选择氧化国家重点实验室，中国科学院兰州化学物理研究所，甘肃兰州，730000。 ;b中国科学院研究生院，北京，100039 ; |
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| 摘 要： | 碘代芳烃与二乙胺在Pd/C催化作用下成功的合成了α-酮酰胺，可以得到非常不错的收率和选择性。在最佳反应条件下，对于不同的碘代芳烃和二级胺都很有很好的底物适应性。
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| 关 键 词： | 双羰化反应 一氧化碳 α-酮酰胺 |
| 收稿时间： | 2008-11-13 |
| 修稿时间： | 2008-12-29 |
Pd/C/PPh3: A Simple and Efficient Catalyst System for Double Carbonylation Reactions |
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| Jianming LIU,Shuzhan ZHENG,Wei SUN,Chungu XIA.Pd/C/PPh3: A Simple and Efficient Catalyst System for Double Carbonylation Reactions[J].Chinese Journal of Chemistry,2009,27(4):623-627. |
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| Authors: | Jianming LIU Shuzhan ZHENG Wei SUN Chungu XIA |
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| Institution: | 1. State Key Laboratory for Oxo Synthesis and Selective Oxidation, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou, Gansu 730000, China;2. Graduate School of the Chinese Academy of Sciences, Beijing 100039, China;3. Tel.: 0086‐0931‐8276531;4. Fax: 0086‐0931‐8277088 |
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| Abstract: | The double carbonylation of iodobenzene and diethylamine proceeds smoothly in the presence of Pd/C and carbon monoxide to afford the corresponding α‐keto amide in good yields with excellent selectivity. In addition, other aryl iodides and secondary amines also react under similar conditions to form α‐keto amides in good yields. |
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| Keywords: | double carbonylation carbon monoxide α‐keto amide |
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