Action of nucleophilic agents on the pyrimidine ring |
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Authors: | A N Kost R S Sagitullin G G Danagulyan |
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Institution: | (1) M. V. Lomonosov Moscow State University, 117234 Moscow |
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Abstract: | It is shown that 2-alkylpyrimidine methiodides in which the alkyl group is activated by electron-acceptor substituents undergo recyclization to the corresponding 2-methylaminopyridines in an alcohol solution of methylamine. Similar recyclization also takes place without quaternization of the pyrimidine ring when there is a strong electron-acceptor substituent (a nitro group) in the ring.Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 10, pp. 1400–1405, October, 1978. |
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