负载型手性钯催化剂的制备和在苯乙酮不对称加氢反应中的应用

在硅烷化硅胶上涂敷手性高分子配位体三苯基氨基甲酸纤维素酯和三（３，５－二甲基苯基氨基甲酸）纤维素酯，然后与ＰｄＣｌ３配位，制备一种新型的负载型不对称加氢催化剂，该催化剂用于苯乙酮的加氢反应，醇收率最高达１００％，但产物的对遇选择性较低的原因。

Preparation of New Supported Chiral Palladium Catalyst and its Application in Asymmetric Hydrogenation of Acetophenone

In this paper study on synthesis of a new supported chiral palladium catalyst was reported. Chiral macromolecular ligands , cellulose triphenylcarbamate and cellulose tris(3,5 dimethylphenyl carbamate), were coated on macroporous siliconited silica gel. The complexation of PdCl 2 with cellulose triphenylcarbamate or cellulose tris (3,5 dimethylphenyl carbamate) formed the title catalysts. These catalysts system were used in asymmetric hydrogenation of acetophenone to sec phenylethyl alcohol, the highest optical yield of 12.3% is obtained when a catalyst system containing cellulose tris(3,5 dimethylphenylcarbamate) was used. Reason of low enantioselectivity of the catalyst was discussed.