|
|||||
|
|
Diastereoselective Coupling of Chiral Acetonide Trisubstituted Radicals with Alkenes |
|
| Authors: | Daniel J. Tao Dr. Mikko Muuronen Yuriy Slutskyy Alexander Le Prof. Filipp Furche Prof. Larry E. Overman |
| Affiliation: | Department of Chemistry, University of California Irvine, Irvine, CA, USA |
| Abstract: | The stereochemical outcome of reactions of chiral nucleophilic trisubstituted acetonide radicals with electron‐deficient alkenes is dictated by a delicate balance between destabilizing non‐bonding interactions and stabilizing hydrogen‐bonding between substituents on the α and β carbons. |
| Keywords: | ab initio calculations alkenes radical reactions stereoselectivity |