Ruthenium(II)‐Catalyzed Traceless C−H Functionalization Using an N−N Bond as an Internal Oxidant |
| |
| Authors: | Dr. Shuguang Zhou Jinhu Wang Pei Chen Kehao Chen Prof. Dr. Jin Zhu |
| |
| Affiliation: | Department of Polymer Science and Engineering, School of Chemistry and Chemical Engineering, State Key Laboratory of Coordination Chemistry, Nanjing National Laboratory of Microstructures, Nanjing University, Nanjing, P. R. China |
| |
| Abstract: | A previously elusive RuII‐catalyzed N?N bond‐based traceless C?H functionalization strategy is reported. An N‐amino (i.e., hydrazine) group is used for the directed C?H functionalization with either an alkyne or an alkene, affording an indole derivative or olefination product. The synthesis features a broad substrate scope, superior atom and step economy, as well as mild reaction conditions. |
| |
| Keywords: | C− H functionalization indoles N− N bond cleavage olefination ruthenium |
|
|
