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A Highly Selective Fluorescence Turn‐On Sensor for Extracellular Calcium Ion Detection |
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| Authors: | Dr. Binglin Sui Xinglei Liu Dr. Mengyuan Wang Prof. Kevin D. Belfield |
| Affiliation: | 1. College of Science and Liberal Arts, New Jersey Institute of Technology, Newark, New Jersey, United States;2. Department of Chemistry, University of Central Florida, Orlando, Florida, United States |
| Abstract: | A highly water‐soluble, fluorescence turn‐on sensor for Ca2+ is reported. The sensor affords high selectivity in sensing Ca2+ over other biologically important metal cations. The dissociation constant of the sensor in binding Ca2+ is 0.92 mm . Fluorescence microscopy experiments demonstrate that the sensor is cell‐impermeable and capable of detecting extracellular Ca2+. |
| Keywords: | calcium cell imaging extracellular calcium detection fluorescence microscopy fluorescence sensors |