Caminoside A,an antimicrobial glycolipid isolated from the marine sponge Caminus sphaeroconia |
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| Authors: | Linington Roger G Robertson Marilyn Gauthier Annick Finlay B Brett van Soest Rob Andersen Raymond J |
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| Affiliation: | Department of Chemistry, University of British Columbia, Vancouver, B.C., V6T 1Z1, Canada. |
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| Abstract: | Extracts of the marine sponge Caminus sphaeroconia showed potent activity in a screen for bacterial type III secretion inhibitors. Bioassay guided fractionation of the extract led to the isolation of the novel antimicrobial glycolipid caminoside A (1). The structure of caminoside A was elucidated by analysis of spectroscopic data and chemical degradation.[structure: see text] |
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