Nickel‐ and Photoredox‐Catalyzed Cross‐Coupling Reactions of Aryl Halides with 4‐Alkyl‐1,4‐dihydropyridines as Formal Nucleophilic Alkylation Reagents |
| |
| Authors: | Dr. Kazunari Nakajima Sunao Nojima Prof. Dr. Yoshiaki Nishibayashi |
| |
| Affiliation: | Department of Systems Innovation, School of Engineering, The University of Tokyo, Tokyo, Japan |
| |
| Abstract: | A combination of nickel and photoredox catalysts promoted novel cross‐coupling reactions of aryl halides with 4‐alkyl‐1,4‐dihydropyridines. 4‐Alkyl‐1,4‐dihydropyridines act as formal nucleophilic alkylation reagents through a photoredox‐catalyzed carbon–carbon (C?C) bond‐cleavage process. The present strategy provides an alternative to classical carbon‐centered nucleophiles, such as organometallic reagents. |
| |
| Keywords: | C− C cleavage cross-coupling dihydropyridines nickel catalysts photoredox catalysts |
|
|
