Catalytic Enantioselective Aza‐Piancatelli Rearrangement |
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| Authors: | Dr Huilin Li Prof Rongbiao Tong Prof Jianwei Sun |
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| Institution: | Department of Chemistry, The Hong Kong University of Science and Technology, Hong Kong SAR, China |
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| Abstract: | An efficient organocatalytic enantioselective aza‐Piancatelli rearrangement is disclosed. The powerful process provides rapid access to valuable chiral 4‐amino‐2‐cyclopentenone building blocks from readily available 2‐furfurylcarbinols with excellent chemo‐, enantio‐, and diastereoselectivities under mild reaction conditions. |
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| Keywords: | asymmetric catalysis carbocycles cyclization organocatalysis rearrangements |
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