Highly Diastereo‐ and Enantioselective Cu‐Catalyzed Borylative Coupling of 1,3‐Dienes and Aldimines |
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| Authors: | Liyin Jiang Prof. Dr. Peng Cao Dr. Min Wang Bin Chen Bing Wang Prof. Dr. Jian Liao |
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| Affiliation: | 1. Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu, China;2. University of Chinese Academy of Sciences, Beijing, China;3. College of Chemical Engineering, Sichuan University, Chengdu, China |
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| Abstract: | A Cu‐catalyzed diastereo‐ and enantioselective borylative coupling reaction of 1,3‐dienes with imines was realized. Branched homoallylic amines are readily prepared in a syn‐selective manner with high regio‐, diastereo‐ and enantioselectivity. Moreover, these three‐component coupling reactions feature good functional‐group compatibility and easy access to the substrates and catalyst. |
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| Keywords: | 1,3-dienes asymmetric catalysis borylative coupling copper imines |
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