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Light‐Controlled Ion Transport through Biomimetic DNA‐Based Channels
Authors:Pei Li  Ganhua Xie  Xiang‐Yu Kong  Zhen Zhang  Kai Xiao  Prof Liping Wen  Prof Lei Jiang
Institution:1. Key Laboratory of Bio-Inspired Smart Interfacial Science and Technology of Ministry of Education School of Chemistry and Environment, Beihang University, Beijing, P.R. China;2. CAS Key Laboratory of Bio-inspired Materials and Interfacial Science, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing, P.R. China;3. Beijing National Laboratory for Molecular Sciences (BNLMS), Key Laboratory of Green Printing, Institute of Chemistry, Chinese Academy of Sciences, Beijing, P.R. China;4. University of Chinese Academy of Sciences, Beijing, P.R. China
Abstract:Light‐controlled nanochannels are fabricated through self‐assembling azobenzene‐incorporated DNA (Azo‐DNA) strands to regulate ion transport. By switching between collapsed and relaxed states using visible and ultraviolet light alternately, the Azo‐DNA channels can be opened and closed because the conformation of Azo‐DNA changes, that is, Azo‐DNA is used as switchable controlling unit. In addition to sharing short response time and reversibility with other photoresponsive apparatuses, the Azo‐DNA‐based nanochannel system has advantages in good biocompatibility and versatile design, which could potentially be applied in light‐controlled drug release, optical information storage, and logic networks.
Keywords:azobenzene  biomimetics  DNA  light control  nanochannels
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