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Applications of Nanopore Sensing in Detection of Toxic Molecules
Authors:Shuo ZHOU  Peng TANG  Yun-Jiao WANG  Liang WANG  De-Qiang WANG
Affiliation:Research Center for Precision Medicine & Single-Molecule Diagnostics, Chongqing Institute of Green and Intelligent Technology, Chinese Academy of Sciences, Chongqing 400714, China
Abstract:As a novel analytical method, nanopore sensing is widely applied in many fields such as nucleic acids sequencing, protein/peptides analysis, detection of metal ions and biomacromolecules including virus, bacteria, etc. With the growing public concerns on dietary safety and public security, there has been a greater demand on the detection of toxic molecules. With high sensitivity and selectivity, nanopore sensing is considered as a more powerful assay, and has been reported in many research articles. Accordingly, this paper surveys the application of nanopore sensing in detection of toxic molecules.
Keywords:Nanopore technology  Single-molecule sensing  Toxic molecules  Sensitivity  Selectivity  Review
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