Green multicomponent reaction for synthesis of trisubstituted pyrroles in ionic liquid [bmim]BF4 |
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| Authors: | G. Narshimha Reddy Pravin R. Likhar |
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| Affiliation: | 1.Organometallic Gp., Inorganic and Physical Chemistry Division,CSIR-Indian Institute of Chemical Technology,Hyderabad,India |
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| Abstract: | 2,4,5-Trisubstituted pyrrole derivatives were efficiently synthesized by one-pot condensation of 1,3-diones, α-bromoacetophenones, and ammonium acetate in ionic liquid [bmim]BF4. The new synthetic method offers multisubstituted pyrroles with the advantages of mild reaction conditions, operational simplicity, higher yield, and environmental friendliness. |
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