Reactions of 5-methylene-1,3-dioxolan-2-ones with amines. Synthesis of 2-oxazolidinones

The reaction of 5-methylene-1,3-dioxolan-2-ones with aromatic or aliphatic amines as well as with the sodium salts of amino acids leads to 4-hydroxy-2-oxazolidinones. The reaction conditions depend on the basicity of the amines. The use of o-phenylenediamine in this reaction leads to the formation of a new heterocyclic system.N. D. Zelinskii Institute of Organic Chemistry, Russian Academy of Sciences, 117913 Moscow; Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 2, pp. 241–251, February, 1999.