Dysfunctional GABAergic inhibition in the prefrontal cortex leading to "psychotic" hyperactivation |
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| Authors: | Shoji Tanaka |
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| Institution: | (1) Department of Information and Communication Sciences, Sophia University, 7-1 Kioicho, Chiyodaku, Tokyo 102-8554, Japan |
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| Abstract: | Background The GABAergic system in the brain seems to be dysfunctional in various psychiatric disorders. Many studies have suggested
so far that, in schizophrenia patients, GABAergic inhibition is selectively but consistently reduced in the prefrontal cortex
(PFC). |
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| Keywords: | |
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