Synthesis and biological evaluation of cytostatin analogues |
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Authors: | Bialy Laurent Waldmann Herbert |
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Affiliation: | Max-Planck-Institut für molekulare Physiologie, Abteilung Chemische Biologie, Otto-Hahn-Str. 11, 44227 Dortmund, Germany. |
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Abstract: | Analogues of the serine/threonine phosphatase 2A inhibitor cytostatin were synthesized and evaluated as inhibitors of various phosphatases in order to establish a basic structure-activity relationship (SAR) of the natural product. |
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