Synthesis, antimicrobial and antifungal activity of double quaternary ammonium salts of biphenyls |
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| Authors: | V K Ol’khovik Yu V Matveienko D A Vasilevskii G V Kalechits R A Zheldakova |
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| Institution: | 1687. Institute of Chemistry of New Materials, National Academy of Sciences of Belarus, ul. Skoriny 36, Minsk, 220141, Belarus
2687. Belarus State University, Minsk, Belarus
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| Abstract: | The synthetic methods for new 2-, 2,2′-, and 3-substituted 4,4′-bis(chloromethyl)biphenyls were developed. Quaternization of them with various amines resulted in a series of new double quaternary ammonium salts containing the biphenyl moiety. The majority of the obtained compounds have a pronounced antifungal and antibacterial activity against the Gram-positive bacteria. |
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