A cyclotrimerization route to cannabinoids |
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Authors: | Teske Jesse A Deiters Alexander |
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Affiliation: | North Carolina State University, Department of Chemistry, Raleigh, North Carolina 27695-8204, USA. |
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Abstract: | Three members of the cannabinoid class, cannabinol, cannabinol methyl ether, and cannabinodiol, were synthesized using a microwave-mediated [2 + 2 + 2] cyclotrimerization reaction as the key step. This approach provides a high level of synthetic flexibility allowing for the facile synthesis of cannabinoid analogues. |
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