Dielectrophoresis based cell switching in continuous flow microfluidic devices |
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| Affiliation: | 1. Department of Mechanical Engineering, College of Engineering, Khalifa University, Abu Dhabi, United Arab Emirates;2. Department of Mechanical Engineering, Korea Advanced Institute of Science and Technology, Daejeon, South Korea;1. Grenoble Institute of Technology (Grenoble-INP), SIMaP, Electromagnetic Processing of Materials (EPM) Group, 38402 Saint Martin d’Hères, France;2. Univ. Grenoble Alpes, SIMaP, 38402 Saint Martin d’Hères, France;1. Key Laboratory of Low-grade Energy Utilization Technologies and Systems, Chongqing University, Chongqing 400030, China;2. Institute of Engineering Thermophysics, Chongqing University, Chongqing 400030, China |
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| Abstract: | This article presents a novel negative-dielectrophoresis based approach for switching of a focused stream of micro-sized particles, including cells, to desired locations inside a continuous flow microfluidic device. The first section, of the device, focuses the incoming stream of micro-sized particles while the second section switches this focused stream of micro-sized particles. The microfluidic device consists of a glass substrate and a PDMS layer. The microfluidic device is realized using standard microfabrication. Tests are carried out using blood cells to demonstrate the efficacy of the approach in switching a stream of micro-sized particles to multiple locations inside the microchannel. |
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| Keywords: | Cells Dielectrophoresis Microchannel Switching Microfluidics Micro-sized particles |
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